Article

Dynamics of Ankylosing Spondylitis-associated Arthritogenic Peptide-MHC I interactions

2023-10-29

Abstract excerpt

Ankylosing spondylitis (AS) is a chronic inflammatory disorder affecting the axial skeleton and often associated with Human Leukocyte Antigen-B*27 (HLA-B*27) positivity. HLA-B*27 and its role in AS pathogenesis remain unclear despite the identification of multiple susceptibility alleles. As the most frequent subtype related to AS, HLA-B*27:05 differs from the non-associated HLA-B*27:09 subtype at a single position...

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Literature Corpus work: 159334ca-190f-5f3c-98ec-c184766d6b16
DOI: 10.21203/rs.3.rs-3474723/v1

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