Article

Five years of SARS CoV-2 Evolution: Implications for RT PCR Diagnostic Performance

2025-10-23

Abstract excerpt

Mutations in SARS-CoV-2 primer/probe target regions can compromise RT-PCR sensitivity, leading to false negatives and undetected viral transmission. This study evaluated mutational landscapes of 20 different primer/probe sets targeting E , N , Orf1b-nsp14 , RdRp , and S genes, using 86,250 high-quality genomes from seven countries. A time-dependent mutational analysis was also conducted through pre-vaccinatio...

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Literature Corpus work: 15933456-4938-5131-958d-1f88095312a6
DOI: 10.22541/au.176124804.46629156/v1

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