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Article

The challenge of screening SARS-CoV-2 variants of concern with RT-qPCR: One variant can hide another.

Journal of virological methods - 1 Nov 2021

Blairon Laurent, Cupaiolo Roberto, Piteüs Sébastien, Beukinga Ingrid, Tré-Hardy Marie

Abstract excerpt

INTRODUCTION: Following the emergence of SARS-CoV-2 variants of concern (VOCs) worldwide, it is important to monitor local epidemiology to better understand the occurrence of clusters, reinfections, or infection after vaccination. Detecting mutations by specific RT-qPCR is a rapid and affordable alternative to sequencing. However, care must be taken to ensure that the techniques used are up-to-date and adapted to...

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Identifiers

PMID: 34332998
DOI: 10.1016/j.jviromet.2021.114248
PMCID: PMC8320429

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