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Article

Multiple assays in a real-time RT-PCR SARS-CoV-2 panel can mitigate the risk of loss of sensitivity by new genomic variants during the COVID-19 outbreak.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Aug 2020

Peñarrubia Luis, Ruiz Maria, Porco Roberto, Rao Sonia N, Juanola-Falgarona Martí, Manissero Davide, López-Fontanals Marta, Pareja Josep

Abstract excerpt

OBJECTIVES: In this study, five SARS-CoV-2 PCR assay panels were evaluated against the accumulated genetic variability of the virus to assess the effect on sensitivity of the individual assays. DESIGN OR METHODS: As of week 21, 2020, the complete set of available SARS-CoV-2 genomes from GISAID and GenBank databases were used in this study. SARS-CoV-2 primer sequences from publicly available panels (WHO, CDC,...

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Identifiers

PMID: 32535302
DOI: 10.1016/j.ijid.2020.06.027
PMCID: PMC7289722

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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