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Increased Collagen V Triggers Inflammation and Fibrosis in Early Pulmonary Disease of Systemic Sclerosis: Insights from the IMU-COLV Model

2025-06-09

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<title>Abstract</title> <p>Understanding the early stages of pulmonary disease pathogenesis in systemic sclerosis (SSc) is crucial for developing therapeutic strategies to mitigate pulmonary fibrosis progression. Our aim is to evaluate the early stages of pulmonary fibrosis in the IMU-COLV model. This study used the SSc IMU-COLV model in female C57BL/6 mice immunized with collagen V (COLV) emulsified in Freund's...

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Literature Corpus work
157fb224-a313-5f42-a242-c1ddeb4f4cb1
DOI
10.21203/rs.3.rs-6814249/v1
Open publication

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Increased Collagen V Triggers Inflammation and Fibrosis in Early Pulmonary Disease of Systemic Sclerosis: Insights from the IMU-COLV ModelDOI 10.21203/rs.3.rs-6814249/v1
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