Article

Pacybara: Accurate long-read sequencing for barcoded mutagenized allelic libraries

2023-02-23

Abstract excerpt

<h4>Summary</h4> Long read sequencing technologies, an attractive solution for many applications, often suffer from higher error rates. Alignment of multiple reads can improve base-calling accuracy, but some applications, e.g. sequencing mutagenized libraries where multiple distinct clones differ by one or few variants, require the use of barcodes or unique molecular identifiers. Unfortunately, sequencing errors...

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Literature Corpus work: 1537f1ea-92d3-5f5d-ba7a-4577401f1b21
DOI: 10.1101/2023.02.22.529427

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