Article

Three-dimensional nuclear telomere architecture and differential expression of aurora kinase genes in chronic myeloid leukemia to measure cell transformation

2022-07-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Telomere dysfunction results in aneuploidy, and ongoing chromosomal abnormalities. The three-dimensional (3D) nuclear organization of telomeres allows for a distinction between normal and tumor cells. On the other hand, aurora kinase genes (<italic>AURKA</italic> and <italic>AURKB</italic>) play an important role regulating the cell cycle. A correlation between...

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Literature Corpus work: 152cd1be-ff82-5d6b-9245-7d649e189cfc
DOI: 10.21203/rs.3.rs-1010489/v1

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