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Integrating TeloView® with Cytogenetics: Biological Characterization of Genomic Instability in CLL Using 3D Telomere Profiling

2026-01-26

Abstract excerpt

Chronic lymphocytic leukemia (CLL) is characterized by recurrent chromosomal abnormalities and variable degrees of genomic instability. Telomere dysfunction contributes to this process, and the three-dimensional (3D) nuclear organization of telomeres reflects structural alterations associated with chromosomal aberrations. The objective of this study was biological characterization rather than prognostication. We i...

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Literature Corpus work
52d83995-b663-56a1-b664-3caea623751b
DOI
10.20944/preprints202601.1919.v1
Open publication

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