Article

Host lung environment limits <i>Aspergillus fumigatus</i> germination through a SskA-dependent signaling response

2021-08-28

Abstract excerpt

<h4>ABSTRACT</h4> Aspergillus fumigatus isolates display significant heterogeneity in growth, virulence, pathology, and inflammatory potential in multiple murine models of invasive aspergillosis. Previous studies have linked the initial germination of a fungal isolate in the airways to the inflammatory and pathological potential; but the mechanism(s) regulating A. fumigatus germination in the airways are unresol...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 151f4167-8e3b-5468-be02-78b8714217e3
DOI: 10.1101/2021.08.27.456493

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Host lung environment limits <i>Aspergillus fumigatus</i> germination through a SskA-dependent signaling responseDOI 10.1101/2021.08.27.456493Read

Host Lung Environment Limits Aspergillus fumigatus Germination through an SskA-Dependent Signaling ResponseSemantic proximity Read

Sporulation environment drives phenotypic variation in the pathogen <i>Aspergillus fumigatus</i>Semantic proximity Read

<i>Aspergillus fumigatus</i> In-Host HOG pathway mutation for Cystic Fibrosis Lung Microenvironment PersistenceSemantic proximity Read

Distinct cohorts of <i>Aspergillus fumigatus</i> transcription factors are required for epithelial damage occurring via contact- or soluble effector-mediated mechanismsSemantic proximity Read

Deletion of core septin gene <i>aspB</i> in <i>Aspergillus fumigatus</i> results in fungicidal activity of caspofunginSemantic proximity Read

Basal UPR activity in <i>Aspergillus fumigatus</i> regulates adaptation to nutrient stress and is critical for the establishment of corneal infectionSemantic proximity Read

Heterogeneity in the transcriptional response of the human pathogen <i>Aspergillus fumigatus</i> to the antifungal agent caspofunginSemantic proximity Read

<i>Candida auris</i> undergoes adhesin-dependent and -independent cellular aggregationSemantic proximity Read

Shaping the fungal adaptome--stress responses of Aspergillus fumigatus.Semantic proximity Read

Aspergillus fumigatus In-Host HOG Pathway Mutation for Cystic Fibrosis Lung Microenvironment Persistence.Semantic proximity Read

Rapid evolution of an adaptive multicellular morphology of Candida auris during systemic infection.Semantic proximity Read

Strain specific persistence in the murine lung of <i>Aspergillus fumigatus</i> conidia causes an Allergic Broncho-Pulmonary Aspergillosis-like disease phenotypeSemantic proximity Read