Article
Shaping the fungal adaptome--stress responses of Aspergillus fumigatus.
International journal of medical microbiology : IJMM - 1 Jun 2011
Hartmann Thomas, Sasse Christoph, Schedler Anette, Hasenberg Mike, Gunzer Matthias, Krappmann Sven
Abstract excerpt
Aspergillus fumigatus as prime pathogen to cause aspergillosis has evolved as a saprophyte, but is also able to infect and colonise immunocompromised hosts. Based on the 'dual use' hypothesis of fungal pathogenicity, general characteristics have to be considered as unspecific virulence determinants, among them stress adaptation capacities. The susceptible, warm-blooded mammalian host represents a specific...
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