Article

Deletion of core septin gene <i>aspB</i> in <i>Aspergillus fumigatus</i> results in fungicidal activity of caspofungin

2025-02-25

Abstract excerpt

Septins are a family of GTP-binding proteins found in many eukaryotic lineages. Although highly conserved throughout many eukaryotes, their functions vary across species. In Aspergillus fumigatus , the etiological agent of invasive aspergillosis, septins participate in a variety of processes, including conidiation, septation, and responses to cell wall stress. Previous studies determined that the Δ aspB strain h...

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Literature Corpus work: 35a90631-6de2-5bb5-a707-ad670c198a67
DOI: 10.1101/2025.02.25.640155

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