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Heterogeneity in the transcriptional response of the human pathogen <i>Aspergillus fumigatus</i> to the antifungal agent caspofungin

2021-07-15

Abstract excerpt

Aspergillus fumigatus is the main causative agent of invasive pulmonary aspergillosis (IPA), a severe disease that affects immunosuppressed patients worldwide. The fungistatic drug caspofungin is the second line therapy against IPA but has increasingly been used against clinical strains that are resistant to azoles, the first line antifungal therapy. In high concentrations, caspofungin induces a tolerance phenotyp...

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Literature Corpus work
6ed2bc94-a074-58ef-9a7d-79c02367381c
DOI
10.1101/2021.07.15.452449
Open publication

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Heterogeneity in the transcriptional response of the human pathogen <i>Aspergillus fumigatus</i> to the antifungal agent caspofunginDOI 10.1101/2021.07.15.452449
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