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Distinct cohorts of <i>Aspergillus fumigatus</i> transcription factors are required for epithelial damage occurring via contact- or soluble effector-mediated mechanisms

2022-04-07

Abstract excerpt

Damage to the lung epithelium is a unifying feature of disease caused by the saprophytic fungus Aspergillus fumigatus . However, the mechanistic basis and the regulatory control of such damage is poorly characterized. Previous studies have identified A. fumigatus mediated pathogenesis as occurring at early (≤ 16 hours) or late (>16 hours) phases of the fungal interaction with epithelial cells, and respectively i...

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Identifiers and source

Literature Corpus work
805a9764-c91c-5eeb-a519-8a45a73a5142
DOI
10.1101/2022.04.07.487466
Open publication

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