Article

Topological analysis of TMEM180, a newly identified membrane protein that is highly expressed in colorectal cancer cells

2019-10-02

Abstract excerpt

New target molecules for diagnosis of and drug development for colorectal cancer (CRC) are always in great demand. Previously, we identified a new colorectal cancer–specific protein, TMEM180, and successfully developed an anti-TMEM180 monoclonal antibody (mAb) for the diagnosis and treatment of CRC. Although TMEM180 is categorized as a member of the cation symporter family and multi-pass membrane protein, little i...

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Literature Corpus work: 15011271-d8d5-5b35-b426-0e23680d7b72
DOI: 10.1101/789750

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