Interactomic exploration of LRRC8A in volume-regulated anion channels

Abstract excerpt

Ion channels are critical in enabling ion movement into and within cells and are important targets for pharmacological interventions in different human diseases. In addition to their ion transport abilities, ion channels interact with signalling and scaffolding proteins, which affects their function, cellular positioning, and links to intracellular signalling pathways. The study of "channelosomes" within cells...

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• Cardiac electrophysiology and arrhythmias
• Ion channel regulation and function
• Ion Channels and Receptors