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Claudin‐1, a Biomarker of Epithelial‐Mesenchymal Transformation, Enhances Lipid Metabolism in Colorectal Cancer Cells to Promote Tumor Metastasis

1 Sept 2025

Abstract excerpt

Claudin-1 (CLDN1), a vital tight junction protein, is linked to epithelial-mesenchymal transition (EMT) of tumor cells. In this study, multi-omics including expression profiles of colorectal cancer (CRC) from The Cancer Genome Atlas (TCGA) dataset, colon expression profiles from the Genotype-Tissue Expression (GTEx) database, and the expression profiles from the Gene Expression Omnibus (GEO) dataset GSE251845...

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Cancer, Lipids, and Metabolism
Cancer-related molecular mechanisms research
Ferroptosis and cancer prognosis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40890958
DOI: 10.1002/jgm.70034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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