Article

The joint-brain axis: evidence from a Mendelian randomization study of osteoarthritis and cortical structure

2024-03-13

Abstract excerpt

<title>Abstract</title> <p>Background Osteoarthritis (OA) is a common joint disease that may affect brain function via a joint-brain axis, but its causal impact on brain cortical structures is unclear. Method We used Mendelian randomization (MR), a method that leverages genetic variants as natural experiments, to examine the effects of OA, including knee and hip OA, on cortical surface area (SA) and thickness (...

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Literature Corpus work: 14b88ebf-9133-5aea-8569-38320adb412c
DOI: 10.21203/rs.3.rs-3993034/v1

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