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Article

Bidirectional Mendelian randomization explores the causal relationship between arthritis and cerebral cortical volume.

Medicine - 15 May 2026

Zhou Yingxia, Sun Fengyu, Peng Dan, Xu Wantong, Zou Qinyu, Jiang Zhongbiao

Abstract excerpt

Mendelian randomization (MR) method was used to explore the causal relationship between the occurrence of arthritis disease and volume changes in specific cerebral cortical regions. By analyzing the genome-wide association studies summary data, single nucleotide polymorphism data related to arthritis and cerebral cortex volume were selected. Using the inverse variance weighted (IVW) method as the preferred...

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Identifiers

PMID: 42152317
DOI: 10.1097/MD.0000000000048788
PMCID: PMC13183111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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