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Article

PELP1/SRC-3-dependent regulation of metabolic kinases drives therapy resistant ER+ breast cancer

2020-08-07

Abstract excerpt

<h4>ABSTRACT</h4> Recurrence of metastatic breast cancer stemming from acquired endocrine and chemotherapy resistance remains a health burden for women with luminal (ER+) breast cancer. Disseminated ER+ tumor cells can remain viable but quiescent for years to decades. Contributing factors to metastatic spread include the maintenance and expansion of breast cancer stem cells (CSCs). Breast CSCs frequently exist as...

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Literature Corpus work
14acfb4b-dd52-5a00-ae2b-6c17d60b9216
DOI
10.1101/2020.08.07.238550
Open publication

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PELP1/SRC-3-dependent regulation of metabolic kinases drives therapy resistant ER+ breast cancerDOI 10.1101/2020.08.07.238550
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