Article
Disease pathogenesis, treatment effectiveness, and co-morbid burden among adult patients with primary immune thrombocytopenia (ITP)
2010-01-01
Abstract excerpt
Background: Primary immune thrombocytopenia (ITP) is an autoimmune disease involving autoantibody-mediated platelet destruction, suboptimal platelet production, and T-cell-mediated platelet lysis. These processes cause a decreased peripheral blood platelet count (< 150 x 109/L), resulting in an increased susceptibility to bleeding events. While thecourse of primary ITP is often acute (< 6 months) among children, i...
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Identifiers and source
- Literature Corpus work
- 1480c8e7-7223-5dcc-b9a1-068ca98edf06
- DOI
- 10.17863/cam.16271