Article

Platelet dysfunction in immune thrombocytopenia: finding clinical subsets with platelet phenotypes

2025-07-16

Abstract excerpt

Patients with immune thrombocytopenia (ITP) remain a challenge to diagnose, manage, and predict bleeding risk. A comprehensive assessment of platelet function may aid clinical management. This study assessed platelet parameters to predict bleeding in ITP. Blood from 103 clinically-annotated cases with isolated thrombocytopenia or 123 healthy donors was evaluated. In the ITP cohort, 75/110 encounters (68%) had plat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e0558e9e-8567-5420-a8a1-1e208e944930
DOI: 10.1101/2025.07.15.25331619

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Platelet dysfunction in immune thrombocytopenia: finding clinical subsets with platelet phenotypesDOI 10.1101/2025.07.15.25331619Read

Immunopathology of immune thrombocytopenia.Semantic proximity Read

Immune Thrombocytopenia: Immune Dysregulation and Genetic Perturbations Deciphering the Fate of Platelets.Semantic proximity Read

Platelet proteo-transcriptomic profiling validates mediators of thrombosis and proteostasis in patients with myeloproliferative neoplasmsSemantic proximity Read

Disease pathogenesis, treatment effectiveness, and co-morbid burden among adult patients with primary immune thrombocytopenia (ITP)Semantic proximity Read

Clinical and laboratorial characterization of a cohort of patients with hereditary platelet disordersSemantic proximity Read

Rare bleeding disorders.Semantic proximity Read

Prothrombotic Phenotype in COVID-19: Focus on Platelets.Semantic proximity Read

Inherited thrombocytopenias: history, advances and perspectivesSemantic proximity Read

Alterations in platelet proteome signature and impaired platelet integrin α <sub>IIb</sub> β <sub>3</sub> activation in patients with COVID-19Semantic proximity Read

Pathogenesis in immune thrombocytopenia: new insights.Semantic proximity Read

Learning the Ropes of Platelet Count Regulation: Inherited ThrombocytopeniasSemantic proximity Read

Molecular Pathogenesis of Inherited Platelet Dysfunction.Semantic proximity Read