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Article

Immune Thrombocytopenia: Immune Dysregulation and Genetic Perturbations Deciphering the Fate of Platelets.

Frontiers in bioscience (Landmark edition) - 26 Sept 2024

Tariq Zahra, Qadeer Muhammad Imran, Zahid Khadija, Cherepkova Elena Vladimirovna, Olzhayev Sayakhat Taurbekovich

Abstract excerpt

Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder. It involves impaired production and excessive destruction of platelets. It is a complex and heterogeneous disorder with unknown pathophysiology. Both genetic and immunologic perturbations have been implicated in the disease pathogenesis. Immune dysregulations involve both the humoral and cellular immunity. Attack of anti-platelet autoantibodies has...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Genetic Predisposition to Disease

Share to Platelet Disorders and Treatments

Share to Polymorphism, Single Nucleotide

Share to Purpura, Thrombocytopenic, Idiopathic

Share to Signal Transduction

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Identifiers

PMID: 39473407
DOI: 10.31083/j.fbl2910342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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