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Clonal hematopoiesis in primary immune thrombocytopenia

15 Mar 2022

Abstract excerpt

Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterized by decreased platelet count and increased risk of bleeding. Clonal hematopoiesis (CH) is described as the expansion of a clonal blood cell population with somatic mutations. It was first raised in a study of X-chromosome inactivation among elderly healthy women [ 1 ], and has been extensively identified in various clinical settings as...

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PMID: 35293382
DOI: 10.1038/s41408-022-00641-5

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