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Gene expression imputation provides insight into the genetic architecture of frontotemporal dementia

2020-06-23

Abstract excerpt

The etiology of genetically sporadic frontotemporal dementia is poorly understood. Although genome-wide association studies for frontotemporal dementia have identified a small number of candidate risk regions, most of the risk genes remain largely unknown. To identify candidate genes with predicted expression levels associated with frontotemporal dementia, we integrated genome-wide summary statistics with external...

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Literature Corpus work
1479e3c8-54dc-5b26-b349-e2d2428b9ad3
DOI
10.1101/2020.06.23.166355
Open publication

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Gene expression imputation provides insight into the genetic architecture of frontotemporal dementiaDOI 10.1101/2020.06.23.166355
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