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DUSP12 regulates NAT10-mediated RNA acetylation to modulate DNA repair and therapeutic response in hepatocellular carcinoma

2026-01-14

Abstract excerpt

Hepatocellular carcinoma (HCC), the most common type of primary liver cancer arising from hepatocytes, is an aggressive hepatic malignancy with limited therapeutic options and poor prognosis. Chemotherapy remains an important treatment for advanced disease, though the mechanisms influencing drug sensitivity remain elusive. This study investigates the role of dual-specificity phosphatase 12 (DUSP12) and its interac...

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Literature Corpus work
1478350a-8da3-5ae4-b063-a197fd93e306
DOI
10.64898/2026.01.10.698822
Open publication

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DUSP12 regulates NAT10-mediated RNA acetylation to modulate DNA repair and therapeutic response in hepatocellular carcinomaDOI 10.64898/2026.01.10.698822
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