Article

Src42A is required for E-cadherin dynamics at cell junctions during <i>Drosophila</i> axis elongation

2022-04-20

Abstract excerpt

Src kinases are important regulators of cell adhesion. Here we explored the function of Src42A in junction remodelling during Drosophila gastrulation. Src42A is required for tyrosine phosphorylation at bicellular and tricellular junctions in germband cells and localizes to hotspots of mechanical tension. The role of Src42A was investigated using maternal RNAi and by CRISPR-Cas9-induced germline mosaics. We find...

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Literature Corpus work: 14741d6f-b21d-5ee1-a9d8-1c83befc1275
DOI: 10.1101/2022.04.20.488907

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