Article

Single-cell RNA Sequencing Reveals Transcriptional Signatures and Cell-cell Crosstalk in Patients With Hypertensive Nephropathy

2021-06-21

Abstract excerpt

<title>Abstract</title> <p>BackgroundHypertensive nephropathy (HTN) is one of the leading causes of end-stage renal disease, yet the precise mechanisms and cell-specific gene expression changes are still unknown. This study used single-cell RNA sequencing (scRNA-seq) to explore novel molecular mechanisms and gene targets for HTN for the first time. <h4>Methods:</h4> The gene expression profiles of renal biopsy sa...

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Literature Corpus work: 4e2d53b0-6ecf-575d-bca8-4dd354f0404f
DOI: 10.21203/rs.3.rs-599634/v1

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