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Article

Selective proliferative response of microglia to alternative polarization signals.

Journal of neuroinflammation - 4 Dec 2017

Pepe Giovanna, De Maglie Marcella, Minoli Lucia, Villa Alessandro, Maggi Adriana, Vegeto Elisabetta

Abstract excerpt

BACKGROUND: Microglia are resident myeloid cells of the central nervous system (CNS) that are maintained by self-renewal and actively participate in tissue homeostasis and immune defense. Under the influence of endogenous or pathological signals, microglia undertake biochemical transformations that are schematically classified as the pro-inflammatory M1 phenotype and the alternatively activated M2 state....

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Identifiers

PMID: 29202771
DOI: 10.1186/s12974-017-1011-6
PMCID: PMC5715534

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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