Article

In Search of the Perfect Model: How Cancer Cell Lines Relate to Native Cancers

2024-05-17

Abstract excerpt

Cancer cell lines are frequently used in biological and translational research to study cellular mechanisms and explore treatment options. However, cancer cell lines may display mutational profiles divergent from native cancers or may be misidentified or contaminated. We explored how similar cancer cell lines are to native cancers to find the most suitable representations for the corresponding diseases by utilisin...

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Identifiers and source

Literature Corpus work: 13e283da-54f6-524f-aa69-05b38e1a7931
DOI: 10.1101/2024.05.15.594310

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