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Matching cancer genomes to established cell lines for personalized oncology.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2011

Dudley Joel T, Chen Rong, Butte Atul J

Abstract excerpt

The diagnosis and treatment of cancers, which rank among the leading causes of mortality in developed nations, presents substantial clinical challenges. The genetic and epigenetic heterogeneity of tumors can lead to differential response to therapy and gross disparities in patient outcomes, even for tumors originating from similar tissues. High-throughput DNA sequencing technologies hold promise to improve the...

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Identifiers

PMID: 21121052
DOI: 10.1142/9789814335058_0026
PMCID: PMC3477496

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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