Article

Elevated oxidative phosphorylation is critical for immune cell activation by polyethylene wear particles

2022-10-21

Abstract excerpt

Chronic inflammation is a major concern after total joint replacements (TJRs), as it is associated with bone loss, limited bone-implant integration (osseointegration), implant loosening and failure. Inflammation around implants could be directed away from adverse outcomes and toward enhanced osseointegration and improved surgical outcome. Activated macrophages exposed to polyethylene particles play a dominant infl...

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Identifiers and source

Literature Corpus work: 139eda73-285a-5792-baaf-34230efcdbfc
DOI: 10.1101/2022.10.19.512774

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