Article

Network reconstruction for trans acting genetic loci using multi-omics data and prior information

2020-05-21

Abstract excerpt

<h4>Background</h4> Molecular multi-omics data provide an in-depth view on biological systems, and their integration is crucial to gain insights in complex regulatory processes. These data can be used to explain disease related genetic variants by linking them to intermediate molecular traits (quantitative trait loci, QTL). Molecular networks regulating cellular processes leave footprints in QTL results as so-cal...

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Literature Corpus work: 1383416e-7389-5f00-8f7d-ebbca283d35e
DOI: 10.1101/2020.05.19.101592

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