Article

Abnormal hypo-methylation of CAP1 (adenylate cyclase associated protein 1) gene enhances biological characteristics of lung adenocarcinoma cells

2023-03-14

Abstract excerpt

<h4>Background: </h4> Lung adenocarcinoma (LUAD) is the most common histological subtype of lung cancer, which is a serious threat to human health. Adenylate cyclase associated protein 1 (CAP1) is an important functional protein, which is closely related to the occurrence and progression of cancer. Methods In this study, we used the CRISPR-dCas9-Dnmt3a system to target the CAP1 promoter to construct LUAD cell str...

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Literature Corpus work: 1357e866-df32-5c74-b37d-0223e7fa39fb
DOI: 10.21203/rs.3.rs-2632990/v1

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