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Targeting the MALAT1 gene with the CRISPR/Cas9 technique in prostate cancer

26 Sept 2022

Abstract excerpt

BACKGROUND: The MALAT1 lncRNA acts as an oncogene in Prostate cancer (PC); thus, it can be severe as a cancer biomarker. METHODS: Using bioinformatics datasets including (HTSeq-Counts, GDC, and TCGA) 5501 gene expression profiling specimens were gathered. Then, expression profiles and sample survival of lncRNA were investigated using COX regression analyses, ROC curve analysis. The Database for Annotation,...

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PMID: 36163080
DOI: 10.1186/s41021-022-00252-3

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