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Article

CAPZA1 Suppressed the Progression of Esophageal Squamous Cell Carcinoma by Binding to hnRNP K and PTPB1 to Influence Its mRNA Stability.

Cancer medicine - 1 Mar 2026

Kang Nan, Ou Yunwei, Guo Shichao, Chen Jie, Li Dan, Zhan Qimin

Abstract excerpt

PURPOSE: Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive and prevalent cancers in China, a deeper understanding at the molecular level is the cornerstone for advancing precision oncology in ESCC. This study aims to investigate the role of CAPZA1 in ESCC progression. Based on our previous whole genome sequencing (WGS) and whole exome sequencing (WES) data indicating frequent copy number...

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Source

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Identifiers

PMID: 41787560
DOI: 10.1002/cam4.71587
PMCID: PMC12963026

Genes

CAPZA1
PTBP1
UPF1
RTCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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