Article
Systematic analysis of gene expression alterations and clinical outcomes of adenylate cyclase-associated protein in cancer.
Oncotarget - 18 Apr 2017
Xie Shuanshuan, Shen Changxing, Tan Min, Li Ming, Song Xiaolian, Wang Changhui
Abstract excerpt
Adenylate Cyclase-associated protein (CAP) is an evolutionarily conserved protein that regulates actin dynamics. Our previous study indicates that CAP1 is overexpressed in NSCLC tissues and correlated with poor clinical outcomes, but CAP1 in HeLa cells actually inhibited migration and invasion, the role of CAP was discrepancy in different cancer types. The present study aims to determine whether CAP can serve as...
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