Article

Fasting Status and Epigenetic Clock Stability: Implications for Aging Research

2026-06-07

Abstract excerpt

<h4>Background</h4> Epigenetic clocks are DNA methylation-based biomarkers increasingly used in aging research and clinical trials. A recent assessment of 18 clocks across multiple short-term perturbations concluded that most demonstrate only moderate biological reliability, raising concerns about their translational utility. However, epigenetic clocks differ substantially in their construction and in the biologi...

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Literature Corpus work: 12e9802c-d460-5090-9251-90894b4ed445
DOI: 10.64898/2026.06.04.729731

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