A systematic review of phenotypic and epigenetic clocks used for aging and mortality quantification in humans.

Abstract excerpt

Aging is the leading driver of disease in humans and has profound impacts on mortality. Biological clocks are used to measure the aging process in the hopes of identifying possible interventions. Biological clocks may be categorized as phenotypic or epigenetic, where phenotypic clocks use easily measurable clinical biomarkers and epigenetic clocks use cellular methylation data. In recent years, methylation clocks...

Topics

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• Aging
• Biological Clocks
• DNA Methylation
• Epigenesis, Genetic
• Mortality