Article
An unbiased comparison of 14 epigenetic clocks in relation to 10-year onset of 174 disease outcomes in 18,859 individuals
2025-07-15
Abstract excerpt
Epigenetic Clocks have been trained to predict chronological age, healthspan and lifespan. Such clocks are often analysed in relation to disease outcomes – typically using small datasets and a limited number of clocks. Here, we present the first large-scale (n=18,849), unbiased comparison of 14 widely used clocks as predictors of 174 incident disease outcomes and all-cause mortality. Second-generation clocks signi...
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Identifiers and source
- Literature Corpus work
- 5c50381f-0293-599b-b561-262c9d0336f9
- DOI
- 10.1101/2025.07.14.25331494