Article

Genetic variants risk assessment for Long QT Syndrome through machine learning and multielectrode array recordings

2025-03-26

Abstract excerpt

<h4>Background</h4> Long QT syndrome (LQTS) is a life-threatening genetic disorder characterized by prolonged QT intervals on electrocardiograms. Congenital forms are mostly associated with variants in the KCNQ1 and KCNH2 genes. Among pathogenic or likely pathogenic (P/LP) variants, some are associated with a significantly higher incidence of cardiac events compared to others. While therapies have significantly re...

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Literature Corpus work: 12a76672-c499-50e3-a1d1-1a5ca582db80
DOI: 10.1101/2025.03.25.25324187

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