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Article

Precision medicine for long QT syndrome: patient-specific iPSCs take the lead.

Expert reviews in molecular medicine - 4 Jan 2023

Yu Yang, Deschenes Isabelle, Zhao Ming-Tao

Abstract excerpt

Long QT syndrome (LQTS) is a detrimental arrhythmia syndrome mainly caused by dysregulated expression or aberrant function of ion channels. The major clinical symptoms of ventricular arrhythmia, palpitations and syncope vary among LQTS subtypes. Susceptibility to malignant arrhythmia is a result of delayed repolarisation of the cardiomyocyte action potential (AP). There are 17 distinct subtypes of LQTS linked to...

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Identifiers

PMID: 36597672
DOI: 10.1017/erm.2022.43
PMCID: PMC10302164

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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