Article

Optogenetic activation of CA1 pyramidal neurons <i>in vivo</i> induces hypersynchronous and low voltage fast seizures

2020-09-09

Abstract excerpt

<h4>ABSTRACT</h4> Increasing evidence supports the idea that the CA1 of the hippocampus plays an important role in the pathogenesis of temporal lobe epilepsy (TLE). There is however a lack of proof that the over-excitation of CA1 alone is sufficient in inducing seizures in vivo . Furthermore, the relevance of the seizures induced from the over-excitation of CA1 to the pathophysiology of TLE is undetermined. Here...

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Literature Corpus work: 929a5557-20df-5b06-9896-8280af02110e
DOI: 10.1101/2020.09.08.288605

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Optogenetic activation of CA1 pyramidal neurons <i>in vivo</i> induces hypersynchronous and low voltage fast seizuresDOI 10.1101/2020.09.08.288605Read

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