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PSEN1 mutant marmoset fibroblasts mimic multi-omic signatures of Alzheimer’s disease

2026-04-28

Abstract excerpt

<h4>ABSTRACT</h4> <h4>INTRODUCTION</h4> The slow, age-related development of Alzheimer’s disease (AD) and inaccessibility of early-stage brain tissue necessitates model studies to understand its origins and progression. Non-human primate models can provide a platform for linking molecular changes to translatable phenotypes. Here, we assess fibroblast lines derived from marmosets with engineered variants in the...

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Literature Corpus work
1267e8d0-fcc4-5925-b59d-093e71da9079
DOI
10.64898/2026.04.24.720222
Open publication

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PSEN1 mutant marmoset fibroblasts mimic multi-omic signatures of Alzheimer’s diseaseDOI 10.64898/2026.04.24.720222
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