Article

Activin A promotes bone fracture repair and acts through a novel myofibroblastic cell population in callus

2022-10-07

Abstract excerpt

Insufficient bone fracture repair represents a significant clinical burden, and identification of novel therapeutics enhancing repair would have substantial clinical and societal impact. Activin A is a TGF-β protein superfamily member known to stimulate ectopic bone formation, but its roles in fracture repair and its therapeutic potentials remain unclear. Using two mouse tibia fracture repair models, here we mappe...

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Identifiers and source

Literature Corpus work: 125ea272-7bda-539a-995a-057d62827c01
DOI: 10.1101/2022.10.05.510962

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