Article
The ameloblastin extracellular matrix molecule enhances bone fracture resistance and promotes rapid bone fracture healing.
Matrix biology : journal of the International Society for Matrix Biology - 1 Jan 2000
Lu Xuanyu, Li Wenjin, Fukumoto Satoshi, Yamada Yoshihiko, Evans Carla A, Diekwisch Tom, Luan Xianghong
Abstract excerpt
The extracellular matrix (ECM) provides structural support, cell migration anchorage, cell differentiation cues, and fine-tuned cell proliferation signals during all stages of bone fracture healing, including cartilaginous callus formation, callus remodeling, and bony bridging of the fracture gap. In the present study we have defined the role of the extracellular matrix protein ameloblastin (AMBN) in fracture...
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