Article
Transcriptional profiling of intramembranous and endochondral ossification after fracture in mice.
Bone - 1 Oct 2019
Coates Brandon A, McKenzie Jennifer A, Buettmann Evan G, Liu Xiaochen, Gontarz Paul M, Zhang Bo, Silva Matthew J
Abstract excerpt
Bone fracture repair represents an important clinical challenge with nearly 1 million non-union fractures occurring annually in the U.S. Gene expression differs between non-union and healthy repair, suggesting there is a pattern of gene expression that is indicative of optimal repair. Despite this, the gene expression profile of fracture repair remains incompletely understood. In this work, we used RNA-seq of two...
Topics
- Animals
- Bony Callus
- Disease Progression
- Female
- Fracture Healing
- Fractures, Bone
- Fractures, Stress
- Gene Expression Profiling
- Gene Expression Regulation
- Gene Ontology
- Membranes