Article

Multidimensional Profiling of Drug-Treated Cells by Imaging Mass Cytometry

2019-02-18

Abstract excerpt

In pharmaceutical research, high-content screening is an integral part of lead candidate development. Drug response in vitro over 40 parameters including biomarkers, signaling molecules, cell morphological changes, proliferation indexes and toxicity in a single sample could significantly enhance discovery of new therapeutics. As a proof of concept, we present a workflow for multidimensional Imaging Mass Cytometry...

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Literature Corpus work: 12538495-d037-550e-b715-9e022db6a916
DOI: 10.1101/549592

Open publication

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