Article
Highly multiplexed phenotypic imaging for cell proliferation studies.
Journal of biomolecular screening - 1 Jan 2014
Cappella Paolo, Gasparri Fabio
Abstract excerpt
The application of multiplexed imaging technologies in phenotypic drug discovery (PDD) enables profiling of complex cellular perturbations in response to drug treatment. High-content analysis (HCA) is among the most pursued approaches in PDD, with a proven capability to identify compounds with a given cellular mechanism of action (MOA), as well as to unveil unexpected drug cellular activities. The ability of...
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