Article
High-content phenotypic profiling of drug response signatures across distinct cancer cells.
Molecular cancer therapeutics - 1 Jun 2010
Caie Peter D, Walls Rebecca E, Ingleston-Orme Alexandra, Daya Sandeep, Houslay Tom, Eagle Rob, Roberts Mark E, Carragher Neil O
Abstract excerpt
The application of high-content imaging in conjunction with multivariate clustering techniques has recently shown value in the confirmation of cellular activity and further characterization of drug mode of action following pharmacologic perturbation. However, such practical examples of phenotypic...
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