Article

RNA-binding protein RBM3 negatively regulates innate lymphoid cells (ILCs) and lung inflammation

2020-07-28

Abstract excerpt

Innate lymphoid cells (ILCs) promote lung inflammation through cytokine production in diseases such as asthma. RNA-binding proteins (RBPs) are critical post-transcriptional regulators of cellular function, including inflammatory responses, though the role of RBPs in innate lymphoid cells is unknown. Here, we demonstrate that RNA-binding motif 3 (RBM3) is one of the most highly expressed RBPs in Thy1.2+ lung ILCs a...

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Literature Corpus work: 11b34009-aab8-586e-bf65-95565a9e443b
DOI: 10.1101/2020.07.27.223958

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